Site-Selective Functionalization of C(sp<sup>3</sup>) Vicinal Boronic Esters

نویسندگان

چکیده

Selective functionalization of the C–B bond in 1,2-bis(boronate) esters has emerged as a powerful tool to prepare 1,2-difunctionalized compounds with stereocontrol. Suzuki cross-coupling, oxidation, amination, and homologation reactions serve platforms wide variety from common intermediate. The exquisite selectivity offered their easy preparation feedstock material using myriad catalytic transformations make them attractive building blocks for complex molecules. In this Perspective, we summarize examples selective vicinal bis(boronates), attending nature functionalization.

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ژورنال

عنوان ژورنال: ACS Catalysis

سال: 2022

ISSN: ['2155-5435']

DOI: https://doi.org/10.1021/acscatal.2c02857